Order Chemotherapy—Details

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  1. Enter the expected date of the visit.

  1. Click OK (ALT+O).

  1. For ambulatory orders, click the select the visit location.

  2. Click OK (ALT+O).

  1. Click to select a treatment.

  2. Click OK (ALT+ O ).

This prompt occurs only if a treatment plan in the LMR is finalized, and only when writing the initial set of chemo orders. The diagnosis and regimen can be changed as needed when writing chemo orders.

  1. A message displays if the patient has chemo orders awaiting activation.

  2. Click OK (ALT+O) to acknowledge.

  3. Click Cancel (ALT+C) unless you are writing orders for another treatment, or unless you are editing active orders.

Protocols are not offered if the patient is not enrolled with Quality Assurance Clinical Trials (QACT) or the MGH Pediatric Protocol registration . See Overview of Chemo Order Entry .

  1. For the initial treatment, select a diagnosis.

  2. If the option is available, select from the Indications drop-down list.

  1. Type the identifying number in the Cycle /Week field, if empty. Press TAB or click the next field to continue.

  1. Type the date of Day 1 or Day 0 of the treatment. Press TAB or click the next field to continue.

  1. For the initial treatment, select a diagnosis.

  2. If you plan to add exception orders, or order from a regimen for an alternate diagnosis, click to check Exception Orders (ALT+E) .

  1. To order from a regimen for an alternate diagnosis:

  1. Select a treatment from the Regimen drop-down list.

  1. If the option is available, select from the Indications drop-down list.

  1. Type the identifying number in the Cycle /Week field, if empty. Press TAB or click the next field to continue.

  1. Type the date of Day 1 or Day 0 of the treatment. Press TAB or click the next field to continue.

Weight and height for chemo calculations is stored separately from any other order entry values—for example, the values used for weight-based dosing of medications ordered outside of a regimen or protocol. Weight must be re-entered every 30 days for oncology patients, every 90 days for patients receiving chemotherapy for other conditions.

Weight entered is outside of the expected range for a patient in this age group.

Height entered is outside of the expected range for a patient in this age group.

If you choose not to use the LMR weight (see Setting Up Treatment—Enter Weight) when there is greater than 5% difference between the LMR and previous COE weight, you must provide a reason for doing so.

  1. Type your reason.

  2. Click OK (ALT+O).

The end of treatment date is calculated by adding the defined length of the existing treatment to its day 1/day 0 date.

  1. Type the reason.

  2. Click OK (ALT+ O ).

  1. If prompted that the standard treatment has been modified since the last time it was ordered for the selected patient and the changes require that you start from the new standard setup:

  1. To access the LMR Oncology Infusion Flowsheet, click Infusion Flowsheet (ALT+F).

To continue writing orders for adult patients, providers who have access to the webLMR must review previously administered chemotherapy by clicking Infusion Flowsheet.

  1. Click OK (ALT+O) to acknowledge the message.

  1. If prompted that orders were discontinued after the session was signed, click OK (ALT+O) to acknowledge the message.

Click OK (ALT+O) to acknowledge the message.

If you want to use the same settings as the orders awaiting approval/authorization, ask the provider who is assigned to sign off.

Click OK (ALT+O) to acknowledge the message.

The chemotherapy medications in the standard regimen have been changed significantly since the previous orders were written. You will not be able to reuse your previous settings. A general care order is added to the set to inform nursing and pharmacy that previous settings did not automatically carry over, and that all dosing should be checked.

Click OK (ALT+O) to acknowledge the message.

The previous set of chemo orders was discarded rather than activated. You cannot reuse the parameters from the discarded orders. Discarded orders cannot be retrieved; the orders must be written from the standard treatment.

Click OK (ALT+ O ).

Physician instructions are defined as needed for the selected regimen or protocol. To review, click the regimen (red) or protocol (purple) folder. Click the Physician Instructions tab if needed.

If the selected treatment is set up with one or more mutually exclusive sets of orders, you are prompted to select one. The player will display the first set of orders in the selected folder.

  1. Click to select an item on the drop-down list.

  2. Click OK (ALT+ O ).

  1. To widen the folder display when the label is long, click Expand (ALT+X). Click Contract (ALT+ N ) to reverse.

  2. Click the yellow folder closedFolder.gif you need if it isn't open yellowFolderOpen.gif .

  3. Click Select (ALT+S).

Confirming previous: If opting to reuse previous orders that have been defined as "single use," you must select a yellow folder. The previous setup will be provided if you select the same folder that was used to write the previous orders.

  1. Click Infusion Flowsheet (ALT+F).

  2. Click Orders in the CAS to return to the chemo player, and LMR to toggle back to the Infusion flowsheet.

  1. The first set of orders is displayed in the orders list. Items that are checked SetCheck.gif are added to the order for the patient.

  1. Click Next (ALT+N) to view another order set.

  1. The final set includes chemotherapy agents and related medications. See Chemo orders—select and edit below for more information.

  2. To complete the orders, having reached the final order set folder, click OK (ALT+O).

  1. If you haven't already, click Next (ALT+N) or Previous (ALT+P) to open the folder with the order to edit, then click the line for an order to select it.

  2. The order's parameters are displayed in the tab sections at the bottom. Click a tab to view its contents.

  3. The summary cannot be changed. If available, type instructions as needed.

  4. Press TAB to update the order display in the list.

  1. If you haven't already, click Next (ALT+N) or Previous (ALT+P) to open the folder with the order to edit, then click the line for an order to select it.

  2. The order's parameters are displayed in the tab sections at the bottom. Click a tab to view its contents.

  3. Select options and type instructions as needed.

  1. Press TAB to update the order display in the list.

  1. If you haven't already, click Next (ALT+N) or Previous (ALT+P) to open the folder with the order to edit, then click the line for an order to select it.

  2. The order's parameters are displayed in the tab sections at the bottom. Click a tab to view its contents.

  3. Select options and type instructions as needed.

Scheduled days can be changed by clicking Other, then clicking the By Day option in the Start day section. When prompted, type the day number(s) as described, then click OK (ALT+ O ).

IV Fluids with the saline lock option selected automatically generate two (2) consequent medication orders on completion. See Overview of Consequent Orders .

  1. Press TAB to update the order display in the list.

  1. If you haven't already, click Next (ALT+N) or Previous (ALT+P) to open the folder to add the order to.

  2. Click Edit (ALT+E). The Orders For This Session scratch pad opens.

  3. Click a button in the session scratch pad to select an order type.

  4. Click Add (ALT+A) or the appropriate order button in the Add New Order section to open the related order form.

  5. Complete the order form and click OK (ALT+O).

  6. Repeat the process for additional orders in that category, then click Close (ALT+C). The new orders are listed in the Orders For This Session scratch pad.

  7. Click Sign (ALT+S).

  8. Type your signing key when prompted, then click OK (ALT+O).

The new orders are checked automatically in the orders list. The next time you or any other authorized clinician writes chemo for this patient, these orders will be available if you opt to reuse the previous orders rather than revert to the standard regimen.

  1. Type the patient's serum creatinine concentration, then press TAB. The creatinine clearance result is calculated automatically based on the CrCl equation required by the treatment.

  2. For exception orders, type the target AUC. To modify a target AUC preset by the regimen or protocol:

  1. Click AUC Modifications (ALT+ M ).

  2. Click to select a modification option.

  3. Click OK (ALT+ O ).

The AUC Dose is calculated automatically when you move to the next entry.

  1. If allowed by the treatment, click one of the two recalculation options.

  1. Click OK (ALT+ O ). The calculated Total Dose is entered automatically.

  1. Type a weight for calculations using customary US or metric units. The alternative units and BSA are calculated automatically.

  2. Click OK (ALT+ O ).

  1. Click either Dose field as appropriate to the dosing you want to change.

  2. If defined for the selected medication, dose changes and reasons are presented in a list box. Click a line in the Choose Dose Modification list to select it.

  1. If dose modifications for a regimen are not presented, type the amount for the dose you want. The new dose cannot be greater than the standard.

  2. The pharmacy does not accept zero (0) doses. If you enter 0 or choose a modification that results in a zero dose, click OK (ALT+ O ) to acknowledge the message. Choose a different dose, or omit the order entirely.

  3. If a reason for the dose modification is not defined, type your reason when prompted.

  4. Click OK (ALT+ O ).

  1. Click the standard dose field.

  2. If correction is needed, type the patient's serum creatinine concentration, then press TAB. The creatinine clearance result is calculated automatically based on the CrCl equation required by the treatment.

  3. For exception orders, type the target AUC. To modify a target AUC preset by the regimen or protocol:

  1. Click AUC Modifications (ALT+ M ).

  2. Click to select a modification option.

  3. If dose modifications are not presented, type the target AUC for the dose you want.

  4. If a reason for the dose modification is not defined, type your reason when prompted.

  5. Click OK (ALT+ O ).

The AUC Dose is calculated automatically when you move to the next entry.

  1. If allowed by the treatment, click one of the two recalculation options.

  1. Click OK (ALT+ O ). The recalculated Total Dose is entered automatically.

  1. Click the standard dose field.

  2. Type the weight to be used in calculating dosing in either pounds (lbs) or kilograms (kg). Alternate units and the BSA are calculated automatically.

  3. Click OK (ALT+ O ). The recalculated Total Dose is entered automatically.

Reasons and orders for dosing options

  1. If you haven't already:

  1. For each dose (up to 6), type an amount. Units are displayed to the left of the field.

  2. For each dose (up to 6), click to select an option from the frequency drop-down list. For Other, type a description when prompted, then click OK (ALT+O).

  3. For each dose (up to 6), type to indicate which day(s) to schedule the dose. Number days before day 1/day 0 as negative (for example, -3); define a range of consecutive days with the first and last day inclusive, and a colon between (for example, starting on day 1, administering each day through 6, is 1:6).

  4. Type instructions as needed.

  5. Click OK (ALT+O).

  6. If the total amount of the dose or doses you ordered does not add up to equal exactly the total dose calculated for the order, you are required to provide a reason. Check that your order is correct.

Orders written for ambulatory care do not transfer to inpatient records, and vice versa. When entering orders for your patient to continue with treatment mid cycle, be aware that the correct day 1 date should be entered upon ordering. This will ensure that the treatment which the patient has received at another facility will not be duplicated upon administration. For example: Your patient began treatment on 1/1/10 and received days 1 and 2 as an outpatient. Your patient is now being admitted to inpatient on day 3 (1/3/10). When writing the inpatient orders, be sure to enter the day 1 date as 1/1/10. If the day 1 date is entered as today, you will need to delete days 1 and 2 from the scheduled days for all applicable orders.

  1. Click the Schedule tab, then click Sched days/doses.

  2. Click the Days (ALT+Y) option.

  3. In the Days field, type numbers separated by commas (,) to designate days of the treatment. There are limits to the changes allowed. Use negative numbers for days prior to a defining event—for example, a bone marrow transplant. To indicate a number of consecutive days, type the first and last day of the range, separated by a colon (:).

  4. If you decrease the number of scheduled days, type the reason when prompted.

  5. Click OK (ALT+ O ).

  1. Click to select an agent from the list.

  2. Click the Do Not Recalculate tab.

  3. Type a reason for preventing recalculation of dosing in the field provided.

  4. Repeat for each chemo medication ordered, as needed.

To queue the order for the allergist team to calculate concentrations, infusion rates, and durations when the patient needs to be desensitized:

  1. Click to select an order from the list.

  2. Click the Desensitize tab.

  3. Click the Desensitize checkbox.

  4. Click the checkbox to affirm that you have discussed the case for desensitization with an allergist.

  1. Click to select an agent from the list.

  2. Click the Instructions tab.

  3. Type in the field provided to add, edit, or remove text.

  4. Repeat for each chemo medication ordered, as needed.

Only chemotherapeutic or chemo-related medications can be added via this form. Dosing methods and scheduling on the Chemo form are set up for chemo and medications that are administered like chemo. To add a different kind of drug, cancel out of this form, click Previous to move to a non-chemo folder, and edit the folder list. See above, Add Orders to a Non-Chemo Set .

  1. Click Add Chemo (ALT+A).

  2. Look up the medication

  1. Type all or part of the name of the medication in the Med name field, then press TAB.

  2. Select an administration method from the Route list to narrow the list of results. Combo or multiple routes are not allowed.

  3. Click Search (ALT+ S ). Results that match your criteria are listed.

  1. Select from the search results

  1. If available, to restart the search based on a different age-based population, click the option at the bottom of the results window.

  2. Press the down arrow key or click a line to select from the displayed list.

  3. Click OK (ALT+ O ) or press ENTER .

  4. If applicable, the IV Type window opens. Click to select an option, then click OK (ALT+ O ).

  1. Define the dosing and other information

  1. Wait a moment for the system to pull up dosing information on the med you selected. Select the method for dosing (dosed by).

  2. Click the Standard Dose field to set the values for calculating the total dose.

  1. Set the schedule

One-time (X1) medications cannot have scheduled days.

  1. Click Scheduled days/doses (ALT+ H ).

  2. Click Days (ALT+Y).

  3. Type numbers separated by commas (,) to designate days of the treatment. Use negative numbers for days prior to a defining event—for example, a bone marrow transplant. To indicate a number of consecutive days, type the first and last day of the range, separated by a colon (:).

  4. Click OK (ALT+ O ) to return to the medications form.

  1. For pediatrics only, as needed define fluids and additives for IV drugs

  1. If you haven't already, click Mix-In... on the Chemo Medication Orders form.  (Fluids and Additives for mix-in are only available for IV routes.)

  2. Select an option from the Fluid drop-down list as the primary diluent. For Other, type a description when prompted, then click OK.

  3. Type the amount of fluid needed.

  4. Select the appropriate unit of measure. For Other, type a description when prompted, then click OK. (Weight-based amounts are calculated automatically when the order is written.)

  5. For each one needed, select from an Additive drop-down list.

  1. If the order needs to be activated by a chemo attending, fellow, NP, or PA, click to check This chemotherapy medication will be administered by the Provider.

  2. For a PO med and an adult patient, to allow the modifications to the administration (to accommodate available tablet strength, or to allow splitting the administration) , click to check Adult PO dose options.

  3. Click OK (ALT+ O ). The order is added to the open Chemo folder.

  1. Type a reason for adding exception orders to the regimen. The reason should include details sufficient for the reviewing oncologist to sign off on the exception.

  2. Click OK (ALT+ O ).

Chemo High Dose—This warning is triggered when the patient's order or orders for a given medication exceed the recommended maximum dose for either the day or the week. If both the daily and the weekly maximum are exceeded, a warning is presented for each. The calculation for total dose includes only those orders entered into the Order Entry system.

  1. Click No, Change Dose (ALT+N) . The player opens to the Chemo folder.

  2. Click the line for the indicated order, then decrease the dose. See Editing chemo orders in the player.

  1. Click Yes, Continue Order (ALT+Y) .

  2. Type a reason for the high dose in the field provided.

  3. Click Close (ALT+C) .

Each order selected is checked to determine if it exceeds the maximum dosing recommendations (see chemo high dose warning, above), if it is listed in the patient's allergy record, and/or if it is likely to interact with any of the patient's current active medication orders or with any of the other orders selected in the regimen/protocol. A separate alert is presented for every order as it is reviewed, for each intervention—drug-drug interactions, allergies, and high dose. In each case, you have the option to remove the order that triggered the alert. You can opt to keep an order that triggers an alert (except for level 1 drug-drug interactions); you must indicate your reasons and course of action for doing so. See also:

  1. Click Memo (ALT+M).

  2. Type to add, edit, or delete the note.

  3. Click OK (ALT+O).

  1. Click Sign (ALT+S).

  2. Define parameters for treatment when prompted.

  1. Select an option and complete as appropriate to indicate whether treatment should be administered based on one or more of the patient's lab results:

  1. Click OK (ALT+O).

  1. Type your signing key.

  2. Assign provider for orders requiring either approval or authorization . To look up a provider:

  1. Type at least three letters of the last name, followed by a comma (,), and one or more letters from the first name (no spaces).

  2. Press ENTER. The Providers list opens, displaying any names that matched your input.

  3. Click to select a name, or press ENTER to take as typed.

  1. Life-Sustaining TreatmentAll inpatients must have orders. If the patient needs and doesn't have active orders for Life-Sustaining Treatment, the three options—Full, Limited, or Unknown—are active beneath the key field. To change from the default of Unknown, click another option.

  2. Click OK (ALT+O).

  3. AllergiesIf there is no allergy information on the patient, the Allergies tab pops to the front.